The San Francisco 49ers vs. Los Angeles Rams game will be played today. Both teams are coming off Week 2 losses and hope to ...

The San Francisco 49ers face the Los Angeles Rams at 1:25 p.m. PDT on Sunday, Sept. 22 at SoFi Stadium in Inglewood, CA.

NFC West foes San Francisco and Los Angeles face off again on Sunday. Here's what to know about one of the oldest rivalries ...

Jimmy Garoppolo knows what it feels like as a San Francisco 49er to come to L.A., but now the quarterback is on the other ...

San Francisco 49ers wide receiver Deebo Samuel will be sidelined the next couple of weeks because of a calf strain he endured ...

NFL Week 3 odds, picks, predictions, TV and streaming information for the Sunday football game between the San Francisco ...

This is the live blog for the San Francisco 49ers' Week 2 road game against the Minnesota Vikings. This will be updated ...

In June, Jefferson signed a record-setting deal with Minnesota. The four-year, $140 million contract extension made Jefferson ...

The 49ers just lost 23-17 on the road to the Minnesota Vikings. Here are the 49ers' grades for this embarrassment.

Looking at Sunday’s San Francisco 49ers at LA Rams Week 3 NFL odds, lines and trends. Here’s what you need to know.

San Francisco 49ers left tackle Trent Williams said he wants to play until he's 40 years old, per NFL on CBS. More News: Jets ...

Analyzing Sunday’s San Francisco 49ers at Los Angeles Rams odds and lines, with expert NFL picks and predictions.