The San Francisco 49ers face the Los Angeles Rams at 1:25 p.m. PDT on Sunday, Sept. 22 at SoFi Stadium in Inglewood, CA.

NFC West foes San Francisco and Los Angeles face off again on Sunday. Here's what to know about one of the oldest rivalries ...

Jimmy Garoppolo knows what it feels like as a San Francisco 49er to come to L.A., but now the quarterback is on the other ...

but it’s the 49ers who still have premium players at left tackle (Trent Williams), receiver (Brandon Aiyuk), linebacker (Fred Warner), cornerback (Deommodore Lenoir) and defensive end (Nick Bosa).

San Francisco 49ers wide receiver Deebo Samuel will be sidelined the next couple of weeks because of a calf strain he endured ...

The Los Angeles Rams will host the San Francisco 49ers for their 2024 home opener at SoFi Stadium, presented by American ...

Add Deebo Samuel to the San Francisco 49ers’ list of injuries woes. The wide receiver will miss “a couple of weeks” due ...

The 49ers woes in Minnesota continued last week when their former quarterback Sam Darnold torched his old squad. The offense ...

The Vikings have had the 49ers’ number the past two years. One of the reasons Minnesota is 2-0 against San Francisco is the presence of defensive coordinator Brian Flores. Flores mixes things up ...

NFL Week 3 odds, picks, predictions, TV and streaming information for the Sunday football game between the San Francisco ...

There’s one very distinct problem facing the San Francisco 49ers’ offense so far in 2024. Thanks in part to an injury to ...